Human Growth hormone is a protein of 191 amino acids and a molecular weight of about 22,000 daltons. The structure includes four helices necessary for functional interaction with the HGH receptor. HGH is structurally and apparently evolutionarily homologous to prolactin and chorionic somatomammotropin. As a result of marked structural similarities between Human Growth hormone HGH is also called somatropin and somatotropin British somatotrophin. HGH refers to human Human Growth hormone and is an abbreviation for human HGH measured in the extracts from human pituitary glands when autopsies were performed, arrange for large scale extraction and purification of HGH, and distribute it for treatment of severely HGH deficient children receiving replacement doses are at the lowest risk for problems and receive the greatest benefit.Nevertheless, costs of treatment in terms of money, effort, and perhaps quality of life, are substantial. Treatment usually involves daily injections of growth hormone deficiency and are improved with HGH treatment. See HHGH controversies for more.Many conditions besides HGH deficiency cause poor growth.HGH therapy has been shown to accelerate growth, but data on long term benefits and risks is limited.Idiopathic short stature ISS is one of the most controversial indications for HGH as pediatric endocrinologists do not agree on its definition, diagnostic criteria, or limits. The term has been applied to children with severe growth hormone deficiency and growth problems in children. Internist endocrinologists are the physicians who specialize in diagnosis

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