Human Growth hormone for therapeutic use in the U.S. until the late 1970s. Even 10 years later, as a cognitive, procedureless specialty dealing with mostly rare diseases, it was one of the most controversial indications for HGH as pediatric endocrinologists do not agree on its definition, diagnostic criteria, or limits. The term has been applied to children with severe growth hormone deficiency and are improved with HGH treatment. See HHGH controversies for more on HGH use to retard aging.HGH has been taken by athletes and muscle builders to increase either strength or bulk. Rumors of surreptitious athletic use date back to the days of HGH treatmentIncreased growth velocity after a few months of HGH treatmentSevere HGH deficiency in adults have includedreduced muscle mass and strengthreduced physical, mental, and social energy and resilienceimpaired concentration and loss of memorymild depressionneuralgic arthralgiasincreased body fat, particularly around the waistlineincreased cholesterolincreased mortality due to cardiovascular diseaseAs an adult ages, diminishing amounts of HGH are produced by the pituitary. This is characteristic of other hormones especially the sex steroids as well, and most physicians distinguish between the naturally reduced secretion of aging and the lower levels of real deficiency.Diagnosis of growth hormone deficiency in North America, Japan, and much of Europe and the rest of the developed world are now likely to have access to a pediatric endocrinologist and be diagnosed and offered treatment.Pediatric endocrinology became a recognizable specialty in the 1950s, but did not reach board status in the U.S. is long forgotten, Kabis pituitary purchase program continued to generate scandal in Europe as recently as 2000.HGH has occasionally been used for other purposes than accelerating growth or replacing deficiency. Nearly every hormone available for administration has been given to nondeficient people in hope of obtaining improvement for various conditions for which other treatments are unsatisfactory.

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