Human Growth hormone for therapeutic use in the U.S. and their manufacturers included Nutropin Genentech, Humatrope Lilly, Genotropin Pfizer, Norditropin Novo, TevTropin Teva and Saizen Serono. The products are nearly identical in composition, efficacy, and cost, varying primarily in the formulations and delivery devices.In the late 1950s Maurice Raben purified enough HGH from human pituitary glands to treat severe HGH deficiency. Physicians trained in the relatively new specialty of pediatric endocrinology provided most of this care, but in the late 1970s a Swedish pharmaceutical company, Kabi, contracted with a number of measurable benefits to severely HGHdeficient adults, such as enhanced energy and strength, and improved bone density. Muscle mass may increase at the expense of adipose tissue. Blood lipid levels improve, but long term mortality benefit has not yet been demonstrated.HGH for severe adult deficiency is usually prescribed.

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